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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERCC6L All Species: 12.08
Human Site: Y1244 Identified Species: 37.96
UniProt: Q2NKX8 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q2NKX8 NP_060139.2 1250 141103 Y1244 M L L T L S L Y K Q L N N N _
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092609 1252 141491 Y1246 M L L T L S L Y K Q L N N N _
Dog Lupus familis XP_549075 1268 143171 Y1262 M L M T L N L Y K Q L N K T _
Cat Felis silvestris
Mouse Mus musculus Q8BHK9 1240 138836
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505482 1393 155753 Y1280 M L L T L G L Y K Q L N R H R
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2BGR3 1451 163208
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P41877 1009 116656
Sea Urchin Strong. purpuratus XP_781405 563 63991
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 97.5 78.8 N.A. 73.4 N.A. N.A. 49.9 N.A. N.A. 44.4 N.A. N.A. N.A. 24.7 22.9
Protein Similarity: 100 N.A. 98.4 85.8 N.A. 82.3 N.A. N.A. 63.8 N.A. N.A. 60 N.A. N.A. N.A. 42.7 33.2
P-Site Identity: 100 N.A. 100 71.4 N.A. 0 N.A. N.A. 73.3 N.A. N.A. 0 N.A. N.A. N.A. 0 0
P-Site Similarity: 100 N.A. 100 85.7 N.A. 0 N.A. N.A. 80 N.A. N.A. 0 N.A. N.A. N.A. 0 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 50 0 0 0 13 0 0 % K
% Leu: 0 50 38 0 50 0 50 0 0 0 50 0 0 0 0 % L
% Met: 50 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 13 0 0 0 0 0 50 25 25 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 50 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 13 % R
% Ser: 0 0 0 0 0 25 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 50 0 0 0 0 0 0 0 0 0 13 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 50 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 38 % _